What is Vemma?

Vemma is a multi-dimensional wellness and clinically studied formula. Our two Gold Standard, 60-person, double-blind, placebo-controlled clinical studies rely on blood draws and thorough analysis of the data of not only the Vemma formula group, but also a placebo (fake) formula group.

The double-blind part means the participants didn’t know what version they were taking, which is one reason why results from a clinical study far outweigh the surveys filled out in an observational study.

Our two studies showed the Vemma formula significantly boosted immune function, significantly decreased CRP (inflammation) and increased antioxidant levels by 18% within two hours, and kept them saturated for 6 hours (blood draws were done at 0, 2, 4 and 6 hour marks).

Vemma shouldn’t be classified solely as a multivitamin. Phytonutrients and glyconutrients, those plant-based compounds from the superfruit mangosteen, green tea and aloe vera, dominate the contents of this formula as well as our 65+ plant-based minerals. The copper and iron minerals used in the mortality study were elemental … a huge difference to plant-based minerals! Our full-spectrum vitamin blend makes up only a small part of a sound overall wellness strategy, and numerous positive studies have confirmed beneficial properties of vitamins.

 

What are Xanthones?

Xanthones are biologically active plant phenols found in a few selected tropical plants. Current research on Xanthones suggests they are beneficial in helping with many conditions including: allergies, infections (microbial, fungus, viral), cholesterol levels, inflammation, skin disorders, gastro-intestinal disorders, and fatigue.

To date, researchers have discovered and classified more than 210 types of Xanthones, 43 types of which are found in the mangosteen fruit. As a matter of fact, Xanthones were first discovered when scientists began studying the health benefits of mangosteen based on its traditional indigenous medical uses. Research into the medicinal properties of Xanthones found in the mangosteen fruit began in the 1970s, and gradually picked up pace as scientists began finding more exciting nutritional properties. Between 1996 and 2005, an exponential amount of research has been done in regards to mangosteen and its Xanthones, and even more studies are in the works. Xanthones have been found to support and enhance the body’s immune system.

Xanthones are powerful antioxidants in a family of phytonutrients, which is beneficial for neutralizing free radicals in the body.

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Facts about Xanthones

The most plentiful natural source of Xanthones is in the mangosteen fruit (Garcinia Mangostana), which contains over 43 types of Xanthones. The mangosteen has by far the most Xanthones of any plants. It is the pericarp of the mangosteen fruit that contains the vast majority of the Xanthones.

Xanthones are some of the most potent antioxidants known. It is thought to be more potent than both Vitamin C and Vitamin E. In fact, many doctors refer to Xanthones as “Super Antioxidants.“…

Xanthones are heat stable molecules. Unlike proteins, they won’t denature or lose their structure when heated.

Xanthones, have been touted by independent researchers to have properties to include anti-inflammatory, anti-convulsant, anti-allergic, anti-tumor, and anti-platelet, to name just a few.

Some of the most important Xanthones found in mangosteen include:

Alpha-mangostin

Beta-mangostin

Gamma-mangostin

Garcinone

Garcinone A

Garcinone C

Garcinone D

Mangostanol

Gartanin

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Medical Properties & Health Benefits of Xanthones

Scientific research has made it abundantly clear that no other fruit compares in its health benefits to mangosteen, due to its Xanthones and other nutritional properties.

The Xanthones function to travel through your body, literally mopping up the free radicals on their way, leaving your body cleaner and healthier than before.

Helping to fight cancer is just one of the many properties that different Xanthones perform. For instance, one study performed in Japan showed that the xanthone alpha-mangostin had apparent properties that suppressed the development of tumors.

Another, performed in China, found the xanthone garcinone E to show significant anti-cancer effects in terms of liver, lung, and gastric cancer cells.

There is also a recent study that has confirmed that gamma mangostin, a xanthones derivative found in the mangosteen, is a potent COX (Cyclooxgenase) 2 inhibitor. The COX 2 enzyme is a chemical in the body that causes inflammation. This enzyme is commonly found in people suffering from joint pain and arthritis.

However, it is also being found with other diseases as well, that are not as obvious, such as Parkinson’s, Alzheimer’s, Cancer and Diabetes. In three separate studies, a Xanthones derivative of the mangosteen slowed down the body’s production of the COX 2 enzyme.

In addition, some Xanthones have shown significant antimicrobial effects in terms of fighting MRSA (methicillin-resistant staphylococcus aureus), which is a bacterial strain known for its tenacious resistance to pharmacologic antibiotics. One scientific study also showed that alpha-mangostin, beta-mangostin, and garcinone B to have pronounced inhibition effects on a strain of tuberculosis.

As if that isn’t enough, Xanthones have also been scientifically proven to help lower LDL, the bad cholesterol, by protecting the LDL from coming into contact with free radicals, thus leaving it unable to oxidize and attach to arterial walls and cause atherosclerosis.

Taking into account the anti-cancer, anti-inflammatory, anti-microbial, and cholesterol-lowering effects of the Xanthones found in mangosteen, there are many other benefits that science has either researched or is in the process of discovering.  You may get the report here.

 

Videos

The information from these videos is based of the research of Dr. J. Frederic Templeman, M.D. and Dr. David A. Morton, Ph.D.

 

1. Mangosteen and Folk Medicine

An introduction to the Mangosteen fruit and describe how it has been used over the centuries in traditional and folk medicine.

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2. Mangosteen and Xanthones

Explaining why Mangosteen is the “X-Factor” to guaranteeing optimal health and speak about the powerful nutrients called XANTHONES.

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3. Mangosteen and Turning a Skeptic

Describes how Dr Templeman was at first skeptical about the mangosteen’s health benefits and talks about the powerful case that turned him around.

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4. Mangosteen and Arthritis

Going into some of the health benefits of the Mangosteen Fruit.

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5. Mangosteen and Cancer

Speaks on the interaction of the Mangosteen with cancer cells.

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6. Mangosteen and Heart Disease

Speaks on the interaction of the Mangosteen and cholesterol and heart disease.

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7. Mangosteen and Bacteria

Talks about the use of Mangosteen to battle infection, particularly addressing the fruit’s anti-bacterial properties.

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8. Mangosteen and The Benefits

Inflammation is a buzz word in the medical community with even some leading experts attributing the causes of major diseases to inflammation. Dr. J. Frederic Templeman, M. D. and Dr. David A. Morton, Ph.D. tie speak on the Mangosteen’s anti-inflammatory properties and how much better it is to use this natural product than it is to risk the potentially severe adverse effects of pharmaceutical products.

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9. Mangosteen and Recommended Usage

Describes how that there are no toxicity factors or other adverse effects when using a natural product like the Mangosteen fruit. They also discuss what they recommend to be the sufficient daily dosage for optimum health.

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10. Mangosteen and The Science

Unlike most of the herbal products and companies available, the Mangosteen is a product that is backed up by scientific research. Dr. J. Frederic Templeman, M. D. and Dr. David A. Morton, Ph.D. make their final statements on the power of this amazing fruit – THE MANGOSTEEN.

 

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Disclaimer: Information herein is not intended to be taken as medical advice. No therapeutic or medical claims are either implied or made. Do not alter any medical treatment or the use of medications without the permission of your medical care provider.

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Reference:

Garcinone E, a xanthone derivative, has potent cytotoxic effect against the patocellular carcinoma cell lines. Planta Med. 2002 Nov;68(11):975-9. Ho CK, Huang YL, Chen CC. Department of Medical Research & Education, Veterans General Hospital, Taipei, ROC.

Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002 Sep;25(9):1137-41. Nakatani K, Atsumi M, Arakawa T, Oosawa K, Shimura S, Nakahata N, Ohizumi Y. Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.

Synthesis and anti-inflammatory effects of xanthone derivatives. J Pharm

Pharmacol. 1996 May;48(5):532-8. Lin CN, Chung MI, Liou SJ, Lee TH, Wang JP. School of Pharmacy, Kaohsiung Medical College, Taiwan, R.O.C.

Immunopharmacological activity of polysaccharide from the pericarp of mangosteen garcinia: phagocytic intracellular killing activities. J Med Assoc Thai. 1997 Sep;80 Suppl 1:S149-54. Chanarat P, Chanarat N, Fujihara M, Nagumo T. Department of Clinical Microscopy, Faculty of Associated Medical Sciences, Chiang Mai University, Thailand.

Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin. Free Radic Res. 2000 Nov;33(5):643-59. Mahabusarakam W, Proudfoot J, Taylor W, Croft K. Chemistry Department, Prince of Songkla University, Hat Yai, Thailand.

Mangostin inhibits the oxidative modification of human low density lipoprotein. Free Radic Res. 1995 Aug;23(2):175-84. Williams P, Ongsakul M, Proudfoot J, Croft K, Beilin L. University of Western Australia, Department of Medicine, Royal Perth Hospital, Australia.

Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection. Planta Med. 1998 Mar;64(2):97-109. Vlietinck AJ, De Bruyne T, Apers S, Pieters LA. Department of Pharmaceutical Sciences, University of Antwerp (UA), Belgium. vlietink@uta.ua.ac.be

Active constituents against HIV-1 protease from Garcinia mangostana. Planta

Med. 1996 Aug;62(4):381-2. Chen SX, Wan M, Loh BN.

Antidiabetic activity of a xanthone compound, mangiferin. Phytomedicine.

2001 Mar;8(2):85-7. Miura T, Ichiki H, Hashimoto I, Iwamoto N, Kato M, Kubo M, Ishihara E, Komatsu Y, Okada M, Ishida T, Tanigawa K. Suzuka University of Medical Science, Mie, Japan.

Synthesis and antithrombotic effect of xanthone derivatives. J Pharm

Pharmacol. 1996 Sep;48(9):887-90. Lin CN, Hsieh HK, Liou SJ, Ko HH, Lin HC, Chung MI, Ko FN, Liu HW, Teng CM. School of Pharmacy, Department of Internal Medicine, Kaohsiung Medical College, Taiwan, R.O.C.

Synthesis and anticonvulsant effects of some aminoalkanolic derivatives of

xanthone. Pharmazie. 1998 Oct;53(10):672-6. Marona H. Department of Chemical Technology of Drugs, Collegium Medicum, Jagiellonian University, Krakow, Poland.

Xanthones as antimalarial agents; studies of a possible mode of action. FEBS

Lett. 1997 Jun 2;409(1):67-73. Ignatushchenko MV, Winter RW, Bachinger HP, Hinrichs DJ, Riscoe MK. Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland 97201, USA.

Alpha-mangostin induces Ca(2+)-ATPase-dependent apoptosis via mitochondrial pathway in PC12 cells. J Pharmacol Sci. 2004 May;95(1):33-40. Sato A, Fujiwara H, Oku H, Ishiguro K, Ohizumi Y. Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.

Antihypertensive and vasorelaxing activities of synthetic xanthone derivatives. Bioorg Med Chem. 2002 Mar;10(3):567-72. Wang LW, Kang JJ, Chen IJ, Teng CM, Lin CN. School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan 807, ROC.

 

 

Vemma Clinical Studies

 

Changes in IL-1α Concentration (Immunity Marker)The purpose of the first independent, randomized, double-blind placebo study evaluated how Vemma enhanced immune function and well-being in humans.* Participants were randomly divided into two groups and received 2 ounces of Vemma or placebo each morning for 30 days. After the 30-day evaluation, the study showed favorable results in immune markers and a lowering of C-reactive protein (CRP) while taking Vemma.*

 

How is Vemma made?

 

 

Product Comparison

How Vemma compares against Thai-Go, Mango-xan, Xango and Naturally Thai Mangosteen.